• Taiwan J Obstet Gynecol · Apr 2015

    Case Reports

    Use of intra-arterial nitroglycerin during uterine artery embolization for severe postpartum hemorrhage with uterine artery vasospasm.

    • Liangcheng Wang, Isao Horiuchi, Yukiko Mikami, Kenjiro Takagi, Tomohisa Okochi, Kohei Hamamoto, Emiko Chiba, and Katsuhiko Matsuura.
    • Perinatal Center, Division of Maternal and Fetal Medicine, Jichi Medical University Saitama Medical Center, Saitama, Japan.
    • Taiwan J Obstet Gynecol. 2015 Apr 1; 54 (2): 187-90.

    ObjectiveUterine artery embolization (UAE) is a standard method for treating postpartum hemorrhage (PPH), although uterine artery vasospasm during UAE may lead to failure of hemostasis. Here, we report our experience with a case of PPH in which the bleeding was successfully controlled by intra-arterial administration of nitroglycerin during the second UAE.Case ReportA 30-year-old woman experienced PPH following a successful cesarean section, and a UAE was performed. However, 6 hours later, vaginal bleeding restarted; the reason for unsuccessful embolization during the first UAE was vasoconstriction due to hypovolemic shock. We performed a second UAE, but uterine bleeding continued. After intra-arterial administration of nitroglycerin, hemostasis was confirmed, and there was no reperfusion of the uterine artery. After these two UAE procedures, no recurrence of bleeding was observed.ConclusionThus, use of intra-arterial nitroglycerin was effective for controlling uterine artery vasospasm during UAE. However, larger studies are required to confirm these findings.Copyright © 2015. Published by Elsevier B.V.

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