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Trans. Am. Clin. Climatol. Assoc. · Jan 2015
ReviewPersonalized Medicine: Genomics Trials in Oncology.
- Daniel F Hayes and Anne F Schott.
- Ann Arbor, Michigan.
- Trans. Am. Clin. Climatol. Assoc. 2015 Jan 1; 126: 133-43.
AbstractThe era of genomics-based medicine promises to provide molecular tests that will permit precision medicine. However, in 2015, it is not clear what the terms genomics-based medicine, molecular tests, or precision medicine mean. In this report, we review the definitions of these terms and other important semantics relative to what it takes to get a tumor biomarker into standard clinical practice, and the potential clinical trial designs that are being considered to determine if tumor biomarker tests based on next-generation sequencing actually provide benefit to patients with cancer.
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