• Dermatology (Basel) · Jan 2020

    Comparative Study

    Comparison of Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Anxiety/Depression Scale (SAS/SDS) in Evaluating Anxiety and Depression in Patients with Psoriatic Arthritis.

    • Tao Yue, Qiting Li, Rongsheng Wang, Zhaoyi Liu, Mengru Guo, Fengmin Bai, Zhanming Zhang, Weifeng Wang, Yahui Cheng, and Haijun Wang.
    • Department of Rheumatology, Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai, China, yuetao0701@163.com.
    • Dermatology (Basel). 2020 Jan 1; 236 (2): 170-178.

    BackgroundThis study aimed to compare the Hospital Anxiety and Depression Scale (HADS) and the Zung Self-Rating Anxiety/Depression Scale (SAS/SDS) in evaluating anxiety and depression in psoriatic arthritis (PsA) patients.MethodsA total of 70 PsA patients were enrolled. Demographic and clinical characteristics were collected after enrollment. HADS-A and SAS were used to evaluate the anxiety of PsA patients, while HADS-D and SDS were used to evaluate the depression of PsA patients.ResultsSimilar results were observed in detecting the rate of anxiety by HADS-A and SAS (27.1 vs. 21.4%, p = 0.424), and there was no difference in classifying the severity of anxiety by HADS-A and SAS (p = 0.347). The Spearman test also disclosed that HADS-A score was positively associated with SAS score (p <0.001). The rates of depression were similar by HADS-D and SDS (27.1 vs. 40.0%; p = 0.108). However, different results were observed in grading the severity of anxiety by HADS-D and SDS (p = 0.009), and no correlation was observed between HADS-D and SDS scores (p = 0.138). The consumption of time for HADS assessment was shorter than that for SAS/SDS assessment (p < 0.001). In addition, a positive correlation of HADS-A score with patients' global assessment (PGA) (p = 0.022) and fatigue scores (p = 0.028) was discovered, and HADS-D score was positively associated with PGA score (p = 0.019). SAS or SDS score presented less correlation with clinical features of PsA patients, which illuminated that only SAS score was positively associated with duration of psoriasis (p = 0.030).ConclusionHADS seems to be a better option for anxiety and depression assessment than SAS/SDS in PsA patients.© 2019 S. Karger AG, Basel.

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