• J Biopharm Stat · Nov 2011

    Comparative Study

    The bootstrap and Markov-chain Monte Carlo.

    • Bradley Efron.
    • Stanford University, Stanford, California 94305, USA. brad@stat.stanford.edu
    • J Biopharm Stat. 2011 Nov 1; 21 (6): 1052-62.

    AbstractThis note concerns the use of parametric bootstrap sampling to carry out Bayesian inference calculations. This is only possible in a subset of those problems amenable to Markov-Chain Monte Carlo (MCMC) analysis, but when feasible the bootstrap approach offers both computational and theoretical advantages. The discussion here is in terms of a simple example, with no attempt at a general analysis.

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