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Case Reports
Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome accompanied by Parkinson's disease.
- Eiichi Ito, Hiroshi Okamoto, Atsuko Mochizuki, Kuniko Ohara, Maiko Kato, Yutaka Terashima, Eiichi Tanaka, Kae Takagi, Shinichiro Uchiyama, and Makoto Iwata.
- Department of Neurology, Neurological Institute, Tokyo Women's Medical University.
- Intern. Med. 2007 Jan 1; 46 (14): 1139-42.
AbstractWe encountered two cases of RS3PE (remitting seronegative symmetrical synovitis with pitting edema) syndrome accompanied by Parkinson's disease (PD). Although the etiology of RS3PE syndrome is still unknown, several possible associations, such as malignancies and viral infections, have been reported; RS3PE syndrome is thought to be an autoimmune-mediated disorder. The present patients did not have any factors which are reported to be associated with RS3PE. Whether or not the complication of PD and RS3PE syndrome is incidental needs to be further examined, and we discuss here the possible cause of association between PD and RS3PE syndrome, including dopamine agonists one of the anti-PD medications.
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