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J. Thromb. Haemost. · Jun 2021
Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology.
- Ishac Nazy, Ulrich J Sachs, Donald M Arnold, Steven E McKenzie, Phil Choi, Karina Althaus, Maria Therese Ahlen, Ruchika Sharma, Rachael F Grace, and Tamam Bakchoul.
- Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
- J. Thromb. Haemost. 2021 Jun 1; 19 (6): 1585-1588.
AbstractVaccine administration is under way worldwide to combat the current COVID-19 pandemic. The newly developed vaccines are highly effective with minimal adverse effects. Recently, the AstraZeneca ChadOx1 nCov-19 vaccine has raised public alarm with concerns regarding the rare, but serious, development of thrombotic events, now known as vaccine-induced immune thrombotic thrombocytopenia (VITT). These thrombotic events appear similar to heparin-induced thrombocytopenia, both clinically and pathologically. In this manuscript, the ISTH SSC Subcommittee on Platelet Immunology outlines guidelines on how to recognize, diagnose and manage patients with VITT.© 2021 International Society on Thrombosis and Haemostasis.
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