• Med. J. Aust. · May 2003

    Case Reports

    Fatal fulminant hepatic failure induced by a natural therapy containing kava.

    • Paul J Gow, Nathan J Connelly, Richard L Hill, Peter Crowley, and Peter W Angus.
    • Gastroenterology Unit, Austin and Repatriation Medical Centre, Melbourne, VIC. paul.gow@armc.org.au
    • Med. J. Aust. 2003 May 5; 178 (9): 442-3.

    AbstractWe describe a case of acute liver failure and death associated with the use of a preparation containing the "natural" anxiolytic kava (Piper methysticum) and passionflower (Passiflora incarnata). The patient died after a report by the Therapeutic Goods Administration (TGA) warning of the potential for hepatotoxicity associated with the use of kava-containing products. The general public and alternative medicine practitioners need to be aware of the potential for non-prescription drugs to cause serious hepatic reactions.

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