• Jaques Sztajnbok, BrasilLucas Mendes Cunha de ResendeLMCRIntensive Care Unit, Emílio Ribas Institute of Infectious Diseases, São Paulo, Brazil., Luis Arancibia Romero, Ana Freitas Ribeiro, Jose Ernesto Vidal, Claudia Figueiredo-Mello, and Ceila Maria Sant' Ana Malaque.
• Intensive Care Unit, Emílio Ribas Institute of Infectious Diseases, São Paulo, Brazil. Electronic address: jaques.sztajnbok@gmail.com.
• Am. J. Med. Sci. 2021 Oct 1; 362 (4): 418-423.

AbstractCoronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and lower-limb ischemia, as well as infarctions of the abdominal viscera, including renal, splenic, and small bowel infarctions. Here, we describe a case of splenic infarction (SI) associated with aortic thrombosis, which evolved despite the prophylactic use of low-molecular-weight heparin (LMWH), in a 60-year-old female patient with COVID-19. The patient was treated clinically with a therapeutic dose of LMWH, followed by warfarin, and eventually presented a favorable outcome. We also present a review of the literature regarding SI in patients with COVID-19.Copyright © 2021 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

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