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Rev Esp Med Nucl Imagen Mol · Mar 2014
Case ReportsAutoimmune lymphoproliferative syndrome and non-Hodgkin lymphoma: what 18F-fluorodeoxyglucose positron emission tomography/computed tomography can do in the management of these patients? Suggestions from a case report.
- A Cistaro, F Pazè, S Durando, M Cogoni, R Faletti, S Vesco, S Vallero, N Quartuccio, G Treglia, and U Ramenghi.
- Positron Emission Tomography Centre, IRMET S.p.A., Euromedic Inc., Turin, Italy. Electronic address: a.cistaro@irmet.com.
- Rev Esp Med Nucl Imagen Mol. 2014 Mar 1; 33 (2): 99-102.
AbstractA young patient with undefined autoimmune lymphoproliferative syndrome (ALPS-U) and low back pain underwent a CT and MRI study that showed enhancing vertebral lesions, some pulmonary nodules and diffuse latero-cervical lymphadenopathy. A (18)F-FDG-PET/CT scan showed many areas of intense (18)F-FDG uptake in multiple vertebrae, in some ribs, in the sacrum, in the liver, in both lungs, in multiple lymph nodes spread in the cervical, thoracic and abdominal chains. A bone marrow biopsy showed a "lymphomatoid granulomatosis", a rare variant of B-cell non-Hodgkin lymphoma (NHL). After the treatment, the (18)F-FDG-PET/CT scan showed a complete metabolic response. Copyright © 2013 Elsevier España, S.L. and SEMNIM. All rights reserved.
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