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- Hiroyasu Yamashiro and Masakazu Toi.
- Dept.of Surgery, Graduate School of Medicine, Kyoto University, Japan.
- Gan To Kagaku Ryoho. 2007 Aug 1; 34 (8): 1173-6.
AbstractTrastuzumab is a recombinant humanized monoclonal antibody directed against HER2. Several issues about its optimal use,mechanism of action or resistance still await convincing answers. Results of large-scale randomized trials and preclinical study might answer these questions. This review summarizes current knowledge about trastuzumab treatment.
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