• Crit Care · Jan 2015

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    Oxygen - a limiting factor for brain recovery.

    • Amir Hadanny and Shai Efrati.
    • Sagol Center for Hyperbaric Medicine and Research, Assaf Harofeh Medical Center, Zerifin, 70300, Israel.
    • Crit Care. 2015 Jan 1; 19: 307.

    AbstractEffective brain metabolism is highly dependent on a narrow therapeutic window of oxygen. In major insults to the brain (e.g., intracerebral hemorrhage), a slight decrease in oxygen supply, as occurs in a hypobaric environment at high altitude, has devastating effects on the injured brain tissue. Conversely, increasing brain oxygenation, by the use of hyperbaric oxygen therapy, can improve brain metabolism and its dependent regenerative processes.

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