• Seminars in oncology · Jun 2016

    Review

    Cutaneous manifestations of lung cancer.

    • Cindy England Owen.
    • University of Louisville, Division of Dermatology, Louisville, KY. Electronic address: ceowen01@louisville.edu.
    • Semin. Oncol. 2016 Jun 1; 43 (3): 366-9.

    AbstractSkin findings can serve as a clue to internal disease. In this article, cutaneous manifestations of underlying lung malignancy are reviewed. Paraneoplastic dermatoses are rare, but when recognized early, can lead to early diagnosis of an underlying neoplasm. Malignancy-associated dermatoses comprise a broad group of hyperproliferative and inflammatory disorders, disorders caused by tumor production of hormonal or metabolic factors, autoimmune connective tissue diseases, among others. In this review, paraneoplastic syndromes associated with lung malignancy are discussed, including ectopic ACTH syndrome, bronchial carcinoid variant syndrome, secondary hypertrophic osteoarthropathy/digital clubbing, erythema gyratum repens, malignant acanthosis nigricans, sign of Leser-Trélat, tripe palms, hypertrichosis lanuginosa, acrokeratosis paraneoplastica, and dermatomyositis.Copyright © 2016 Elsevier Inc. All rights reserved.

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