• J Am Acad Audiol · Feb 2005

    Comparative Study

    Sensitivity of distortion product otoacoustic emissions in noise-exposed chinchillas.

    • Bob Davis, Wei Qiu, and Roger P Hamernik.
    • Auditory Research Laboratory, Plattsburgh State University of New York, Plattsburgh, New York 12901, USA. Robert.Davis@plattsburgh.edu
    • J Am Acad Audiol. 2005 Feb 1; 16 (2): 69-78.

    AbstractThe present study investigates the effect of small amounts of outer hair cell (OHC) loss on distortion product otoacoustic emission (DPOAE) levels and evoked potential permanent threshold shifts (PTS) in a population of 12 noise-exposed chinchillas. The group mean DPOAE level, which decreased by up to approximately 15 dB in the presence of less than 8 dB PTS and 15% OHC loss, indicates that DPOAEs can detect an underlying cochlear pathology (i,e., OHC damage/loss) despite the presence of normal to near normal thresholds. The sensitivity of DPOAEs in detecting OHC loss makes this test measure suited for diagnosing sensorineural hearing impairment, particularly when abnormal auditory symptoms (i.e., speech discrimination problems) are associated with a normal audiogram in the clinical setting and as part of a hearing conservation program.

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