• James K Min, Charles A Taylor, Stephan Achenbach, Bon Kwon Koo, Jonathon Leipsic, Bjarne L Nørgaard, Nico J Pijls, and Bernard De Bruyne.
• Departments of Radiology and Medicine, Weill Cornell Medical College, New York, New York; Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, New York, New York. Electronic address: jkm2001@med.cornell.edu.
• JACC Cardiovasc Imaging. 2015 Oct 1; 8 (10): 1209-1222.

AbstractFractional flow reserve derived from coronary computed tomography angiography enables noninvasive assessment of the hemodynamic significance of coronary artery lesions and coupling of the anatomic severity of a coronary stenosis with its physiological effects. Since its initial demonstration of feasibility of use in humans in 2011, a significant body of clinical evidence has developed to evaluate the diagnostic performance of coronary computed tomography angiography-derived fractional flow reserve compared with an invasive fractional flow reserve reference standard. The purpose of this paper was to describe the scientific principles and to review the clinical data of this technology recently approved by the U.S. Food and Drug Administration. Copyright © 2015 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

20 keywords...

hide…