• J. Matern. Fetal. Neonatal. Med. · Oct 2011

    Review

    Weaning from mechanical ventilation.

    • Camilla Gizzi, Corrado Moretti, and Rocco Agostino.
    • NICU-S. Giovanni Calibita Hospital Fatebenefratelli, Isola Tiberina-Rome, Italy. camillagizzi@tin.it
    • J. Matern. Fetal. Neonatal. Med. 2011 Oct 1;24 Suppl 1:61-3.

    AbstractMechanical ventilation is often required by very preterm infants with respiratory failure, even if invasive respiratory support is related to lung injury and adverse neurologic outcomes. The exposure to mechanical ventilation should be therefore limited. Optimal extubation however remains challenging, as approximately 30% of intubated preterm infants fails attempted extubation due to poor respiratory drive, atelectasis, residual pulmonary function abnormalities or intercurrent illness. This review outlines the advantages of different weaning strategies that should be considered by neonatologists for current use to reduce unsuccessful extubation.

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