• Magn Reson Imaging · Sep 2005

    An improved 3-D Look--Locker imaging method for T(1) parameter estimation.

    • Ken Nkongchu and Giles Santyr.
    • Department of Physics, Herzberg Laboratories, Carleton University, Ottawa ON, Canada K1S 5B6. knkongch@physics.carleton.ca
    • Magn Reson Imaging. 2005 Sep 1; 23 (7): 801-7.

    AbstractThe 3-D Look-Locker (LL) imaging method has been shown to be a highly efficient and accurate method for the volumetric mapping of the spin lattice relaxation time T(1). However, conventional 3-D LL imaging schemes are typically limited to small tip angle RF pulses (5 degrees ), thereby improving the SNR and the accuracy of the method. In phantom studies, a mean T(1) measurement accuracy of less than 2% (0.2-3.1%) using a tip angle of 10 degrees was obtained for a range of T(1) from approximately 300 to 1,700 ms with a measurement time increase of only 15%. This accuracy compares favorably with the conventional 3-D LL method that provided an accuracy between 2.2% and 7.3% using a 5 degrees flip angle.

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