• Clin Nephrol · Oct 1998

    Case Reports

    Uremic small artery disease: calciphylaxis with penis involvement.

    • S P Handa and D Strzelczak.
    • Department of Pathology, Atlantic Health Sciences Corporation, Saint John, N.B., Canada.
    • Clin Nephrol. 1998 Oct 1; 50 (4): 258-61.

    AbstractTwo male patients with chronic renal failure maintained on hemodialysis developed progressive clinical features of ischemic necrosis (so called calciphylaxis) of their extremities and penis. Both patients died. In one patient, penectomy provided tissue for histopathologic examination and there were changes of small artery calcification. A role of iron overload on the production of calciphylaxis is reviewed. This report is perhaps the first in nephrology literature on the occurrence of calciphylaxis involving penis and prepuce.

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