• Medicina clinica · Jan 2022

    Review

    Irritable bowel syndrome.

    • Juan J Sebastián Domingo.
    • Servicio de Aparato Digestivo, Hospital Royo Villanova, Zaragoza, España. Electronic address: jjsebastian@salud.aragon.es.
    • Med Clin (Barc). 2022 Jan 21; 158 (2): 76-81.

    AbstractIrritable bowel syndrome is one of the most common functional bowel disorders, and has a substantial impact on patients' daily lives, as well as a big economic impact on society. It is characterised by abdominal pain, bloating and abdominal distention and altered bowel movements, with a predominance of diarrhoea, constipation, or alternation of these signs, which cannot be explained by a structural or biochemical abnormality. Its aetiopathogenesis and pathophysiological mechanism are unknown. The disease affects 5%-10% of healthy individuals at any given time and, in most people, has a relapsing-remitting course. This article reviews some of the main and most current evidence on its epidemiology, risk factors, pathophysiology, clinical manifestations, diagnostic approach, and therapeutic options, both dietary, pharmacological and psychotherapeutic.Copyright © 2021 Elsevier España, S.L.U. All rights reserved.

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