• Oncology reports · Apr 2006

    Phase I study of S-1 and biweekly docetaxel combination chemotherapy for advanced and recurrent gastric cancer.

    • Ikuo Takahashi, Yasunori Emi, Yoshihiro Kakeji, Eriko Tokunaga, Shin Ushiro, Eiji Oki, Masayuki Watanabe, Hideo Baba, and Yoshihiko Maehara.
    • Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan. takahashii@matsuyama.jrc.or.jp
    • Oncol. Rep. 2006 Apr 1; 15 (4): 849-54.

    AbstractA phase I study of S-1 and biweekly docetaxel (DOC) combination therapy was conducted to determine the maximum tolerated dose (MTD) and pharmacokinetic parameters. Fourteen patients with advanced or recurrent gastric cancer were analyzed. The treatment consisted of S-1 [body surface area (BSA) <1.25 m2:80 mg/day, 1.25

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