• Clin Med (Lond) · Oct 2016

    Case Reports

    An extreme case of platypnoea-orthodeoxia syndrome.

    • Kevin O'Gallagher, Evelyn Chou, Swarna Jeyabraba, Aish Sinha, Daniel Robb, and Jonathan Byrne.
    • specialty registrar in interventional cardiology, King's College Hospital NHS Foundation Trust, London, UK drkogallagher@gmail.com.
    • Clin Med (Lond). 2016 Oct 1; 16 (5): 453454453-454.

    AbstractAn 80-year-old female presented with progressive breathlessness, worse on sitting or standing and relieved by lying flat. Subsequent investigations identified a patent foramen ovale (PFO) with right-to-left flow across the interatrial septum (IAS). A diagnosis of platypnoea orthodeoxia syndrome secondary to inter-atrial shunting was made. Technical features precluded a percutaneous PFO closure so an open surgical repair was performed with complete resolution of symptoms. We discuss the pathophysiology and management of platypnoea orthodeoxia syndrome.© Royal College of Physicians 2016. All rights reserved.

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