• Semin Pediatr Neurol · Sep 1995

    Review

    Selected leukodystrophies.

    • J M Powers and A Rubio.
    • Department of Pathology and Laboratory Medicine, University of Rochester Medicine Center, NY 14642, USA.
    • Semin Pediatr Neurol. 1995 Sep 1; 2 (3): 200-10.

    AbstractThe clinicopathologic profiles of the major leukodystrophies (adreno-leukodystrophy, metachromatic leukodystrophy, globoid cell leukodystrophy or Krabbe's disease, Pelizaeus-Merzbacher disease, and spongy degeneration of infancy or Canavan's disease) are reviewed. Particular attention is paid to distinctive imaging characteristics, molecular advances, pathogeneses, and potential therapies.

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