• Revue médicale de Liège · Mar 2009

    Review Case Reports

    [Esthesioneuroblastoma: a case report and literature review].

    • L Kalala, C Focan, F Schils, R Gilles, F Abraham, P Reginster, and D Van Den Berge.
    • Service d'Oncologie Médicale, CHC, Clinique Saint Joseph, Liège, Belgique.
    • Rev Med Liege. 2009 Mar 1; 64 (3): 119-23.

    AbstractEsthesioneuroblastoma (ENB) or olfactive neuroblastoma is a rare cancer arising from the neuroepithelium of the olfactory epithelium of the nasal cavity. Sinusal, orbital and intracranial expansions are common. The anatomopathological diagnosis will frequently require immuno-histochemical tests and sometimes electron-microscopy as well as genetic testing. Medical imaging with CT scan and MRI is essential for the stadification. Treatment will generally associate debulking or curative surgery (with combined rhino-neurosurgical accesses) and conformal stereo-tactic radiotherapy. Chemotherapy was generally reserved for palliative cases; it can be now proposed as neoadjuvant treatment. Most patients will relapse; thus the follow-up will remain ad vitam.

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