• J. Cell. Physiol. · Aug 2019

    Review

    Therapeutics for advanced hepatocellular carcinoma: Recent advances, current dilemma, and future directions.

    • Jing Zhu, Tailang Yin, Yong Xu, and Xiao-Jie Lu.
    • Department of General Surgery, Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, The Sparkfire Scientific Research Group of Nanjing Medical University, Nanjing, China.
    • J. Cell. Physiol. 2019 Aug 1; 234 (8): 12122-12132.

    AbstractHepatocellular carcinoma (HCC) is one of the most common malignancies and is a serious threat to people's health worldwide. The prognosis of advanced HCC is dim if left untreated. In the clinic, the treatment options for advanced HCC include surgery, radiotherapy, transcatheter arterial chemoembolization, and so forth. In recent years, molecular targeted therapy and immunotherapy have also made great progress, bringing new hope to patients with advanced HCC. In this study, therapeutic advances, current dilemma, and future directions of advanced HCC are reviewed, which might serve as a summary for clinicians and may stimulate future research.© 2019 Wiley Periodicals, Inc.

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