• Maturitas · May 2020

    Randomized Controlled Trial

    Effectiveness of transcutaneous tibial nerve stimulation at two different thresholds for overactive bladder symptoms in older women: a randomized controlled clinical trial.

    • Aline Teixeira Alve, Azevedo GarciaPatríciaPUniversity of Brasília, Centro Metropolitano, Conjunto A, Lote 0, Universidade De Brasília - Campus Ceilândia, Zip-code: 72220-90 Brasília, DF, Brazil. Electronic address: patriciagarcia@unbr.br., Raquel Henriques Jácomo, Batista de SousaJoãoJUniversity of Brasilia, Hospital Universitário De Brasília SGAN 605, Av. L2 Norte Clínica Cirúrgica Zip-code: 70.840-901 Brasília, DF, Brazil. Electronic address: sousajb@unb.br., Lara Borges Gullo Ramos Pereira, Liana Barbaresco Gomide Mateus, and Margô Gomes de Oliveira Karnikoskwi.
    • University of Brasilia, Centro Metropolitano, Conjunto A, Lote 01, Universidade De Brasília - Campus Ceilândia, Zip-code: 72220-90 Brasília, DF, Brazil. Electronic address: alinealves@unb.br.
    • Maturitas. 2020 May 1; 135: 40-46.

    ObjectivesTo compare the effectiveness of transcutaneous tibial nerve stimulation (TTNS) at two different current amplitude thresholds (sensory and motor) in terms of urinary habit, symptoms and the degree of discomfort of overactive bladder (OAB) in older women.Study DesignThis is a randomized, controlled, 3-arm blinded trial. One hundred and one patients attending secondary care with OAB were randomized into one of three groups: group 1, TTNS sensitivity threshold (n = 39); group 2, TTNS motor threshold (n = 33); and control group 3 (n = 29).Main Outcome MeasuresParticipants allocated to groups 1 and 2 had 8 sessions of TTNS for 30 min, twice a week. Group 3 received no intervention. The results measured were the symptoms of overactive bladder (ICIQ-OAB, overall score), bother scales (to indicate the impact of individual symptoms for the patient) and urinary habit (3-day bladder diary). A blind assessor measured outcomes at baseline and 5 weeks after randomization.ResultsAfter five weeks, a statistically significant difference between group 3 (control) and group 1 (TTNS sensitivity threshold) and group 2 (TTNS motor threshold) was observed in the intergroup analysis, but no difference in the outcomes analyzed was detected between the two groups receiving intervention (groups 1 and 2).ConclusionTTNS is effective in the treatment of OAB in older women, with no difference between the sensitivity and motor thresholds.Clinical Trial Registration NumberRegistro Brasileiros de Ensaios Clínicos (RBR-39DZ5V).Copyright © 2020 Elsevier B.V. All rights reserved.

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