• J. Thromb. Haemost. · May 2018

    Variation of renal function over time is associated with major bleeding in patients treated with direct oral anticoagulants for atrial fibrillation.

    • C Becattini, M Giustozzi, M G Ranalli, G Bogliari, F Cianella, M Verso, G Agnelli, and M C Vedovati.
    • Internal and Cardiovascular Medicine - Stroke Unit, University of Perugia, Perugia, Italy.
    • J. Thromb. Haemost. 2018 May 1; 16 (5): 833-841.

    AbstractEssential In patients on treatment with direct anticoagulants (DOACs) variation of renal function is common. The effect of variations of renal function over time on major bleeding is not well defined. Variation of renal function over time is an independent predictor of major bleeding. Identifying conditions associated with variation of renal function may increase safety of DOACs.© 2018 International Society on Thrombosis and Haemostasis.

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