• Med Sci Law · Oct 2020

    Flubromazolam: Detection in five post-mortem cases.

    • Kemba Abdul, Laura Hikin, Paul Smith, Hassan Kurimbokus, Emily Ashong, Lewis Couchman, and Stephen R Morley.
    • University Hospital of the West Indies, Jamaica.
    • Med Sci Law. 2020 Oct 1; 60 (4): 266-269.

    AbstractFlubromazolam is a potent triazole benzodiazepine with moderately long-lasting central nervous system-depressant effects relative to other benzodiazepines such as commonly prescribed diazepam. Flubromazolam has been studied in the living. However, there are no published reports including measured drug concentrations in post-mortem cases. We report five cases in which flubromazolam was detected in a systematic screen using high-resolution mass spectrometry and then quantified in femoral blood. In none of the five cases was the cause of death directly attributed to flubromazolam toxicity, as there was a variety of both sedative and stimulant drugs also present. However, it is important that the drug concentrations that were measured are made available for future post-mortem forensic interpretation.

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