• Ann Fr Anesth Reanim · Oct 2007

    Review

    [Closed-loop titration of propofol guided by the bispectral index].

    • N Liu, T Chazot, B Trillat, G A Dumont, and M Fischler.
    • Service d'anesthésie, hôpital Foch, 40, rue Worth, 92151 Suresnes, France.
    • Ann Fr Anesth Reanim. 2007 Oct 1;26(10):850-4.

    AbstractThis review analyzes the clinical studies concerning the automated perfusion, or closed-loop, of propofol guided by the bispectral index (BIS). To carry out the maintenance of general anaesthesia by a closed loop propofol-BIS is feasible as shown by studies comprising few low risk patients. We showed that induction of anaesthesia is feasible with a closed loop, haemodynamic stability being similar to a manual titration. A second study, bearing on the whole of the anaesthesia of patients ASA I to III undergoing very diverse surgical acts, showed that the closed loop propofol-BIS was more precise than a manual perfusion. This confirms that the closed loop propofol-BIS is not an esoteric research and that it represents a tool with a future for the clinician.

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