• Best Pract Res Clin Obstet Gynaecol · Oct 2020

    Review

    Management of viral hepatitis A, C, D and E in pregnancy.

    • Mimi Tin-Yan Seto, Ka Wang Cheung, and HungIvan F NIFNDepartment of Medicine, The University of Hong Kong, Hong Kong SAR, China..
    • Department of Obstetrics and Gynaecology, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China. Electronic address: mimiseto@hku.hk.
    • Best Pract Res Clin Obstet Gynaecol. 2020 Oct 1; 68: 44-53.

    AbstractViral hepatitis can cause significant maternal and neonatal morbidity and mortality. Hepatitis A and E mainly present as acute hepatitis during pregnancy, while hepatitis C and D are usually found as chronic infection in pregnant women. Hepatitis A remains self-limiting during pregnancy while hepatitis E has a higher prevalence and manifests with a rigorous course in pregnant women. Screening of hepatitis C during pregnancy and its subsequent management during pregnancy are still a debatable topic. New treatments of hepatitis C and E require further evaluation for use in pregnancy. This review summarizes the prevalence, clinical manifestations, maternal, foetal and neonatal effects, and the management of hepatitis A, C, D and E viral infection during pregnancy.Copyright © 2020. Published by Elsevier Ltd.

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