• Archives of virology · Mar 2021

    Randomized Controlled Trial Multicenter Study

    Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study.

    • Hany M Dabbous, Sherief Abd-Elsalam, Manal H El-Sayed, Ahmed F Sherief, Fatma F S Ebeid, El GhafarMohamed Samir AbdMSADepartment of Anesthesia, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt., Shaimaa Soliman, Mohamed Elbahnasawy, Rehab Badawi, and Mohamed Awad Tageldin.
    • Tropical Medicine Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
    • Arch. Virol. 2021 Mar 1; 166 (3): 949-954.

    AbstractNo specific antiviral drugs have been approved for the treatment of COVID-19. This study aimed to evaluate the efficacy of favipiravir in treatment of COVID-19. This was a multicenter randomized controlled study including 96 patients with COVID- 19 who were randomly assigned into a chloroquine (CQ) group and a favipiravir group. None of the patients in the favipiravir group needed mechanical ventilation (p = 0.129). One patient (2.3%) in the favipiravir group and two patients (4.2%) in the CQ group died (p = 1.00). Favipiravir is a promising drug for COVID-19 that decreases the hospital stay and the need for mechanical ventilation.ClinicalTrials.gov Identifier NCT04351295.

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