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Review Case Reports
Bilateral Adrenal Infarctions as an Initial Manifestation of TAFRO Syndrome: A Case Report and Review of the Literature.
- Shun Yonezaki, Kazuya Nagasaki, Hiroyuki Yamaguchi, and Hiroyuki Kobayashi.
- Department of Internal Medicine, Mito Kyodo General Hospital, University of Tsukuba, Japan.
- Intern. Med. 2022 Mar 1; 61 (5): 743-747.
AbstractTAFRO syndrome is a systemic inflammatory disorder resembling multicentric Castleman disease; it is characterized by thrombocytopenia, anasarca, a fever, reticulin fibrosis, and organomegaly. Involvement of the adrenal glands, including adrenal infarction, hemorrhaging, and adrenomegaly, has recently been reported in several cases and been considered a characteristic early-stage symptom. We herein report a case of TAFRO syndrome initially presenting with bilateral adrenal infarctions and review the literature on TAFRO syndrome related to adrenal involvement. This case suggests that adrenal abnormalities as an early clinical feature of TAFRO syndrome may be useful for the early diagnosis.
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