• Ann. Clin. Lab. Sci. · Jan 2004

    Influence of smoking on maternal and neonatal serum malondialdehyde, superoxide dismutase, and glutathione peroxidase levels.

    • Bahri Ermis, Rahmi Ors, Abdulkadir Yildirim, Ayhan Tastekin, Fatih Kardas, and Fatih Akcay.
    • Department of Pediatrics, School of Medicine, Zonguldak Karaelmas University, 67600 Kozlu/Zonguldak, Turkey. bahriermis@yahoo.com
    • Ann. Clin. Lab. Sci. 2004 Jan 1; 34 (4): 405-9.

    AbstractThis cohort study investigated postnatal serum malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione peroxidase (GPx) levels in 14 active-smoking, 14 passive-smoking, and 15 non-smoking mothers and their newborns on day 7 post-partum. No significant differences were noted among the study groups with respect to MDA (p = 0.63) or SOD levels (p = 0.98) in either the mothers or their infants. However, there were significant differences among the study groups with respect to serum GPx activities in both the mothers (p = 0.028) and the infants (p = 0.039). When GPx activities were analyzed separately in both mothers and infants, a significant difference was noted only between the infants of smoking mothers and the infants of non-smoking mothers (p = 0.015). In conclusion, there was a significant increase in GPx activities of smoking mothers and their infants, suggesting that they may have been exposed to more oxidant stress.

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