• J Affect Disord · Jul 1999

    Comparative Study

    Symptomatologic analysis of psychotic and non-psychotic depression.

    • E Lattuada, A Serretti, C Cusin, M Gasperini, and E Smeraldi.
    • Istituto Scientifico H. San Raffaele, Department of Neuroscience, University of Milan, School of Medicine, Italy.
    • J Affect Disord. 1999 Jul 1;54(1-2):183-7.

    BackgroundThe aim of the present study is to evaluate the symptomatologic presentation of delusional compared to non-delusional major depressive episodes.MethodsTwo hundred and eighty-eight subjects suffering from mood disorder (144 bipolar, 133 unipolar) were assessed at admission by the Hamilton Depression Rating Scale (HAMD-21).ResultsDepressive symptomatology was more severe in the delusional sample, even after the exclusion of the items directly involved with delusional symptoms (P = 0.00002).ConclusionsOur data support the hypothesis of delusional depression as a more severe form of mood disorder.

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