• Elke Lodewijckx, Cindy Kenis, Johan Flamaing, Philip Debruyne, Inge De Groof, Christian Focan, Frank Cornélis, Vincent Verschaeve, Christian Bachmann, Dominique Bron, Sylvie Luce, Gwenaelle Debugne, Heidi Van den Bulck, Jean-Charles Goeminne, Dirk Schrijvers, Katrien Geboers, Benedicte Petit, Christine Langenaeken, Ruud Van Rijswijk, Pol Specenier, Guy Jerusalem, Jean-Philippe Praet, Katherine Vandenborre, Jean-Pierre Lobele, Koen Milisen, Hans Wildiers, and Lore Decoster.
• Department of Medical Oncology, Oncologisch Centrum, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
• J Geriatr Oncol. 2021 Apr 1; 12 (3): 368-374.

BackgroundThis study aims to investigate the occurrence of unplanned hospitalizations in older patients with cancer and to determine predictive factors.MethodsA prospective Belgian multicentre (n = 22), observational cohort study was performed. Patients ≥70 years with a malignant tumor were included. Patients underwent G8 screening followed by geriatric assessment (GA) if abnormal at baseline and were followed for unplanned hospitalizations at approximately three months. Uni- and multivariable regression models were performed to determine predictive factors associated with unplanned hospitalizations in older patients with an abnormal G8.ResultsIn total, 7763 patients were included in the current analysis of which 2409 (31%) patients with a normal G8 score and 5354 (69%) with an abnormal G8 score. Patients with an abnormal G8 were hospitalized more frequently than patients with a normal G8 (22.9% versus 12.4%; p < 0.0001). Reasons for unplanned hospitalizations were most frequently cancer related (25.7%) or cancer therapy related (28%). In multivariable analysis, predictive factors for unplanned hospitalizations in older patients with cancer and an abnormal G8 were female gender, absence of surgery, chemotherapy, ADL dependency, malnutrition and presence of comorbidities.ConclusionOlder patients with cancer and an abnormal G8 screening present a higher risk (23%) for unplanned hospitalizations. Predictive factors for these patients were identified and include not only patient and treatment related factors but also GA related factors.Copyright © 2020 Elsevier Inc. All rights reserved.

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