• Internal medicine · Mar 2022

    Case Reports

    Nodular Pulmonary Amyloidosis Associated with Sjögren's Syndrome.

    • Yoshiaki Kinoshita, Takato Ikeda, Takuto Miyamura, Yusuke Ueda, Yuji Yoshida, Mitsuharu Ueda, Seiji Haraoka, Hisako Kushima, and Hiroshi Ishii.
    • Department of Respiratory Medicine, Fukuoka University Chikushi Hospital, Japan.
    • Intern. Med. 2022 Mar 15; 61 (6): 877-881.

    AbstractAmyloidosis is a rare disease characterized by the deposition of abnormal proteins in extracellular tissues. We herein report a case with instructive radiologic features of nodular pulmonary amyloidosis associated with Sjögren's syndrome. A 67-year-old woman was referred to our department because of an abnormal chest radiograph. Chest computed tomography revealed multiple round cysts accompanied by calcified nodules. The patient was clinically diagnosed with primary Sjögren's syndrome and pathologically diagnosed with nodular pulmonary amyloidosis (light chain, kappa). Although multiple lung cysts have many etiologies, the presence of calcified nodules associated with multiple lung cysts is useful for narrowing down the differential diagnosis.

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