• Am. J. Hypertens. · May 2014

    Comparative Study Clinical Trial

    Invasive validation of arteriograph estimates of central blood pressure in patients with type 2 diabetes.

    • Niklas Blach Rossen, Esben Laugesen, Christian Daugaard Peters, Eva Ebbehøj, Søren Tang Knudsen, Per Løgstrup Poulsen, Hans Erik Bøtker, and Klavs Würgler Hansen.
    • Department of Medicine, Silkeborg Regional Hospital, Silkeborg, Denmark.
    • Am. J. Hypertens. 2014 May 1; 27 (5): 674-9.

    BackgroundCentral blood pressure (BP) has attracted increasing interest because of a potential superiority over brachial BP in predicting cardiovascular morbidity and mortality. Several devices estimating central BP noninvasively are now available. The aim of our study was to determine the validity of the Arteriograph, a brachial cuff-based, oscillometric device, in patients with type 2 diabetes.MethodsWe measured central BP invasively and compared it with the Arteriograph-estimated values in 22 type 2 diabetic patients referred to elective coronary angiography.ResultsThe difference (invasively measured BP minus Arteriograph-estimated BP) in central systolic BP (SBP) was 4.4±8.7 mm Hg (P = 0.03). The limits of agreement were ±17.1 mm Hg.ConclusionsCompared with invasively measured central SBP, we found a systematic underestimation by the Arteriograph. However, the limits of agreement were similar to the previous Arteriograph validation study and to the invasive validation studies of other brachial cuff-based, oscillometric devices. A limitation in our study was the large number of patients (n = 14 of 36) in which the Arteriograph was unable to analyze the pressure curves. In a research setting, the Arteriograph seems applicable in patients with type 2 diabetes.Clinical Trail RegistrationClinicalTrials.gov ID NCT01538290.

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