• Rev Col Bras Cir · Feb 2016

    Randomized Controlled Trial

    Enhanced muscle strength with carbohydrate supplement two hours before open cholecystectomy: a randomized, double-blind study.

    • Marcella Giovana Gava, Heloísa Michelon Castro-Barcellos, Cervantes Caporossi, and Aguilar-NascimentoJosé Eduardo deJEFaculdade de Medicina, Universidade Federal de Mato Grosso, Cuiabá, MT, Brasil..
    • Faculdade de Medicina, Universidade Federal de Mato Grosso, Cuiabá, MT, Brasil.
    • Rev Col Bras Cir. 2016 Feb 1; 43 (1): 54-9.

    Objectiveto investigate the effects of preoperative fasting abbreviation with oral supplementation with carbohydrate in the evolution of grip strength in patients undergoing cholecystectomy by laparotomy.Methodswe conducted a clinical, randomizeddouble blind study with adult female patients, aged 18-60 years. Patients were divided into two groups: Control Group, with fasting prescription 6-8h until the time of operation; and Intervention Group, which received prescription of fasting for solids 6-8h before surgery, but ingested an oral supplement containing 12.5% carbohydrate, six (400ml) and two (200ml) hours before theprocedure. The handgrip strength was measured in both hands in both groups, at patient's admission (6h before surgery), the immediate pre-operative time (1h before surgery) and 12-18h postoperatively.Resultswe analyzed 27 patients, 14 in the intervention group and 13 in the control group. There was no mortality. The handgrip strength (mean [standard deviation]) was significantly higher in the intervention group in the three periods studied, in at least one hand: preoperatively in the dominant hand (27.8 [2.6] vs 24.1 [3.7] kg; p=0.04), in the immediate preoperative in both hands, and postoperatively in the non-dominant hand (28.5 [3.0] vs 21.3 [5.9] kg; p=0.01).Conclusionthe abbreviation of preoperative fasting to two hours with drink containing carbohydrate improves muscle function in the perioperative period.

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