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Case Reports
Dysautonomia as the Presenting Symptom in Anti-Muscle-Specific Kinase Antibody Myasthenia Gravis.
- BekooijT J STJSDepartment of Neurology, Haaglanden Medical Centre Westeinde, The Hague, The Netherlands., H J Gilhuis, L Dawson, and E H Niks.
- Department of Neurology, Haaglanden Medical Centre Westeinde, The Hague, The Netherlands.
- J Neuromuscul Dis. 2020 Jan 1; 7 (1): 47-50.
AbstractIn an minority of Myasthenia Gravis (MG) patients, the autoantibodies bind to muscle-specific kinase (MUSK). These MuSK antibody-mediated MG (MuSK MG) patients are not only immunologically distinct, but also have different characteristic clinical features. Dysautonomia in MG is rarely reported. We present a MuSK MG patient who suffered from life-threatening autonomic dysfunction. MuSK MG should be considered in the differential diagnosis in cases of unclarified dysautonomia, given the potential for treatment in those cases.
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