• Farm Hosp · Nov 2007

    Practice Guideline

    [Summary of the GEIPC-SEIMC and GTEI-SEMICYUC recommendations for the treatment of infections caused by gram positive cocci in critical patients].

    • P M Olaechea Astigarraga, J Garnacho Montero, S Grau Cerrato, O Rodríguez Colomo, M Palomar Martínez, R Zaragoza Crespo, P Muñoz García-Paredes, E Cerdá Cerdá, F Alvarez Lerma, Study Group on Infections in Critical Patients, and INfectious Diseases Working Group.
    • Servicio de Medicina Intensiva, Hospital de Galdakao, Vizcaya, GEIPC, Spain. pedromaria.olaecheaastigarraga@osakidetza.net
    • Farm Hosp. 2007 Nov 1; 31 (6): 353-69.

    ObjectiveIn recent years there has been an increase in infections caused by gram-positive cocci in critical patients, together with a rapid development of resistance to the antibiotics which are normally used to treat them. The objective is to prepare an antibiotic treatment guide for the most common infections caused by gram positive cocci in critical patients. This guide will help in the decision-making process regarding the care of such patients.MethodExperts from two scientific societies worked together to prepare a consensus document. They were members of the Study Group on Infections in Critical Patients (GEIPC), which is part of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), and the Infectious Diseases Working Group (GTEI), belonging to the Spanish Society of Intensive Care Medicine and Coronary Units (SEMICYUC). There was a systematic review of the literature published up to September 2006 regarding this type of infections and the antibiotic treatments marketed to that date. An evidence grading system was applied according to the strength of the recommendation (categories A, B or C) and the level of evidence (categories I, II or III). Recommendations were given if there was consensus among the experts from both societies.ResultsThe antibiotic regimens recommended for treating infections caused by gram-positive cocci were presented in the form of tables, showing the recommendation grade. Alternatives were given for allergic patients. The scientific basis supporting the aforementioned recommendations is explained within the text and the references upon which they are based are cited.ConclusionsA summary of an evidence-based practical guide for the treatment of infections caused by gram-positive cocci in critical patients is presented.

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