• Der Internist · Nov 2021

    Review

    [Renal insufficiency in the context of cardio-pulmonary-renal pathophysiology].

    • Vedat Schwenger, Insa E Emrich, Felix Mahfoud, Jörg Latus, and Andrew Remppis.
    • Klinik für Nieren‑, Hochdruck- und Autoimmunerkrankungen, Klinikum der Landeshauptstadt Stuttgart gKAöR, Katharinenhospital, Kriegsbergstr. 60, 70174, Stuttgart, Deutschland. sekretariat.schwenger@klinikum-stuttgart.de.
    • Internist (Berl). 2021 Nov 1; 62 (11): 115311651153-1165.

    AbstractHeart failure and renal insufficiency as well as pulmonary hypertension are pathophysiologically closely associated as a cardio-renal or cardio-pulmonary-renal syndrome. Due to the frequent hospitalization of patients affected by this syndrome, it is of high medical and also health economic relevance. Besides the inhibition of the renin-angiotensin-aldosterone system (RAAS), multimodal treatment options are available with mineralocorticoid receptor antagonists, angiotensin receptor-neprilysin inhibitors and sodium-glucose transporter 2 (SGLT-2) inhibitors. Profound knowledge of the pathophysiology and the therapeutic options is as necessary for an optimized medical care as patient-oriented, transdisciplinary and cross-sectoral care.© 2021. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

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