• Transl Res · Dec 2013

    Review

    Telomeres in lung disease.

    • John M Gansner and Ivan O Rosas.
    • Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass. Electronic address: jgansner@partners.org.
    • Transl Res. 2013 Dec 1; 162 (6): 343-52.

    AbstractTelomeres are DNA-protein structures that cap the ends of chromosomes; telomerase is the enzyme that ensures their integrity. Telomere biology has recently been implicated in the pathogenesis of a variety of lung diseases, including idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease/emphysema, and lung cancer. This review highlights recent discoveries pertaining to the role of telomere biology in lung disease. Copyright © 2013 Mosby, Inc. All rights reserved.

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