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JACC Cardiovasc Interv · Dec 2015
Multicenter Study Observational StudyRegional Systems of Care to Optimize Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement.
- Dion Stub, Sandra Lauck, May Lee, Min Gao, Karin Humphries, Albert Chan, Anson Cheung, Richard Cook, Della SiegaAnthonyADivision of Cardiology, Royal Jubilee Hospital, Victoria, British Columbia, Canada., Jonathon Leipsic, Jay Charania, Danny Dvir, Tim Latham, Jopie Polderman, Simon Robinson, Daniel Wong, Christopher R Thompson, David Wood, Jian Ye, and John Webb.
- Centre for Heart Valve Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada; Division of Cardiology, Alfred Hospital, Western Health, Baker IDI Heart and Diabetes Institute, Melbourne Australia.
- JACC Cardiovasc Interv. 2015 Dec 28; 8 (15): 1944-1951.
ObjectivesThis study sought to describe the development of a multicenter, transcatheter aortic valve replacement program and regional systems of care intended to optimize coordinated, efficient, and appropriate delivery of this new therapy.BackgroundTranscatheter aortic valve replacement (TAVR) has become an accepted treatment option for patients with severe aortic stenosis who are at high surgical risk. Regional systems of care have led to improvements in outcomes for patients undergoing intervention for myocardial infarction, cardiac arrest, and stroke. We implemented a regional system of care for patients undergoing TAVR in British Columbia, Canada.MethodsWe describe a prospective observational cohort of 583 patients who underwent TAVR in British Columbia between 2012 and 2014. Regionalization of TAVR care in British Columbia refers to a centrally coordinated, funded, and evaluated program led by a medical director and a multidisciplinary advisory group that oversees planning, access to care, and quality of outcomes at the 4 provincial sites. Risk-stratified case selection for transfemoral TAVR is performed by heart teams at each site on the basis of consensus provincial indications. Referrals for lower volume and more complicated TAVR, including nontransfemoral access and valve-in-valve procedures, are concentrated at a single site. In-hospital and 30-day outcomes are reported.ResultsThe median age was 83 years (interquartile range [IQR]: 78 to 87 years) and median STS score was 6% (IQR: 4% to 8%). Transfemoral access was performed in 499 (85.6%) cases and nontransfemoral in 84 (14.4%). Transcatheter valve-in-valve procedures in for failed bioprosthetic valves were performed in 43 patients (7.4%). A balloon-expandable valve was inserted in 386 (66.2%) and a self-expanding valve in 189 (32.4%). All-cause 30-day mortality was 3.5%. All-cause in-hospital mortality and disabling stroke occurred in 3.1% and 1.9%, respectively. Median length of stay was 3 days (IQR: 3 to 6 days), with 92.8% of patients discharged directly home.ConclusionsThis experience demonstrates the potential benefits of a regional system of care for TAVR. Excellent outcomes were demonstrated: most patients had short in-hospital stays and were discharged directly home.Copyright © 2015 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
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