• Pain · Jun 2022

    Decrease in pain perception during acute SARS-CoV-2 infection: a case series.

    • Lisa Hentsch, Patrick Stancu, Gilles Allali, Karl-Olof Lövblad, Johannes A Lobrinus, Sara Cocetta, Sophie Pautex, Marjolaine Uginet, Jacques Serratrice, and Matteo Coen.
    • Division of Palliative Medicine, Geneva University Hospitals, Geneva, Switzerland.
    • Pain. 2022 Jun 1; 163 (6): 101910221019-1022.

    AbstractMany reports have described pain appearance or an increase of chronic pain concomitant to severe acute respiratory syndrome coronavirus 2 infection. Here, we describe the cases of 3 patients with chronic cancer pain, in which COVID-19 was associated with a dramatic reduction or disappearance of pain. Pain reappeared after recovery from COVID-19. Neurological imaging and pathological findings, when available, were inconclusive. To the best of our knowledge, this is the first case series reporting an acute reduction in pain perception in COVID-19. We believe further investigation is mandatory because it could shed new light on the mechanisms of pain perception and modulation.Copyright © 2021 International Association for the Study of Pain.

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