• J. Cardiovasc. Electrophysiol. · Mar 2009

    Clinical Trial

    Electrophysiologic characteristics of complex fractionated atrial electrograms in patients with atrial fibrillation.

    • Jae H Park, Hui-Nam Pak, Sook K Kim, Jin K Jang, Jong I Choi, Hong E Lim, Chun Hwang, and Young-Hoon Kim.
    • Korea University Cardiovascular Center, Seoul, Republic of Korea.
    • J. Cardiovasc. Electrophysiol. 2009 Mar 1; 20 (3): 266-72.

    IntroductionThe underlying mechanisms of complex fractionated atrial electrogram (CFAE) during radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) have not yet been clearly elucidated. We explored the relationships between CFAE and left atrial (LA) voltage, or conduction velocity (CV).Methods And ResultsIn 50 patients with AF (23 paroxysmal AF [PAF], 41 males, mean age 55.76 +/- 10.16 years), the CFAE (average index of fractionation of electrograms during AF by interval-analysis algorithm, cycle length [CL]ConclusionsThe CFAE area, which is primarily located at the septum, has a low voltage with a lower CV, and is surrounded by high-voltage areas. Underlying electroanatomical complexity is associated with clustering of CFAEs.

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