• Appl Psychophysiol Biofeedback · Jun 2007

    Randomized Controlled Trial

    Targeting pCO(2) in asthma: pilot evaluation of a capnometry-assisted breathing training.

    • Alicia E Meuret, Thomas Ritz, Frank H Wilhelm, and Walton T Roth.
    • Department of Psychology, Southern Methodist University, Dallas, TX 75205, USA. ameuret@smu.edu
    • Appl Psychophysiol Biofeedback. 2007 Jun 1;32(2):99-109.

    ObjectivesThis pilot study aimed to evaluate the feasibility and potential benefits of a novel biofeedback breathing training for achieving sustained increases in pCO(2) levels.MethodsTwelve asthma patients were randomly assigned to an immediate 4-week treatment group or waiting list control. Patients were instructed to modify their respiration in order to change levels of end-tidal pCO(2) using a hand-held capnometer. Treatment outcome was assessed in frequency and distress of symptoms, asthma control, lung function, and variability of peak expiratory flow (PEF).ResultsWe found stable increases in pCO(2) and reductions in respiration rate during treatment and 2-month follow-up. Mean pCO(2) levels rose from a hypocapnic to a normocapnic range at follow-up. Frequency and distress of symptoms was reduced and reported asthma control increased. In addition, mean PEF variability decreased significantly in the treatment group.ConclusionsOur pilot intervention provided evidence for the feasibility of pCO(2)-biofeedback training in asthma patients.

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