[Management and follow-up of acute myeloblastic leukemia with

Revista médica de Chile · Jun 2021

Case Reports

[Management and follow-up of acute myeloblastic leukemia with translocation (8; 21). Report of one case].

We describe the management and follow-up of a 20-year-old male with acute myeloblastic leukemia with translocation (8; 21) [t (8; 21)]. A quantitative polymerase chain reaction for t(8; 21) in bone marrow was performed at diagnosis and after three consolidations with high doses of cytarabine. Currently, the management of this type of leukemias has been oriented towards the early detection of relapse. The concept of minimal or measurable residual disease, as the burden of leukemia cells that persist undetected, is an important tool in the therapeutic decision and follow-up of these patients.

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- José Salinas-Laval, Gerardo Alarcón, Luis Leyton, and Blaz Lesina.
- Subdepartamento de Medicina, Hospital Base Valdivia, Valdivia, Chile.
- Rev Med Chil. 2021 Jun 1; 149 (6): 945-949.
AbstractWe describe the management and follow-up of a 20-year-old male with acute myeloblastic leukemia with translocation (8; 21) [t (8; 21)]. A quantitative polymerase chain reaction for t(8; 21) in bone marrow was performed at diagnosis and after three consolidations with high doses of cytarabine. Currently, the management of this type of leukemias has been oriented towards the early detection of relapse. The concept of minimal or measurable residual disease, as the burden of leukemia cells that persist undetected, is an important tool in the therapeutic decision and follow-up of these patients.

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[Management and follow-up of acute myeloblastic leukemia with translocation (8; 21). Report of one case].

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