• Pediatric transplantation · Jun 2005

    Sirolimus for solid organ transplantation in children.

    • Puneet Gupta, Stuart Kaufman, and Thomas M Fishbein.
    • Georgetown University Hospital, Transplant Institute, Washington, DC 20007, USA. pg63@gunet.georgetown.edu
    • Pediatr Transplant. 2005 Jun 1; 9 (3): 269-76.

    AbstractSirolimus represents a major advancement in the field of solid organ transplantation and is being used as a rescue agent for acute and chronic rejection as well as for primary immunosuppression with good graft outcome. Although initial studies with sirolimus were in adults, now significant data have accumulated on the role of sirolimus in pediatric solid organ transplantation. This article reviews the current status of sirolimus in pediatric transplantation.

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