• N Heaton, W Faraj, H Vilca Melendez, W Jassem, P Muiesan, G Mieli-Vergani, A Dhawan, and M Rela.
• Institute of Liver Studies, King's College London School of Medicine at King's College Hospital, Denmark Hill, London SE5 9RS, UK. nigel.heaton@kingsch.nhs.uk
• Br J Surg. 2008 Jul 1; 95 (7): 919-24.

BackgroundLiving related liver transplantation (LRLT) has become established for treating children with end-stage liver disease. The aim of this study was to review a single-centre experience of left lateral segment liver transplants from living donors in children.MethodsFifty left lateral segment LRLT procedures have been performed since 1993. There were 17 girls and 33 boys, of median age 1.5 years (range 0.5 to 13 years), with a median weight of 10 (range 0.7-44) kg. Donors included 23 mothers, 26 fathers and one uncle, with a median age of 33 (range 19-46) years.ResultsAt a median follow-up of 86 months, there was no donor mortality and low morbidity. Patient and graft survival rates were 98, 96 and 96 per cent, and 98, 96 and 93 per cent at 1, 3 and 5 years respectively. Three children had a second transplant at a median of 9 years after the first. The incidence of hepatic artery thrombosis, portal vein thrombosis and biliary complications was 6, 4 and 14 per cent respectively.ConclusionLiving related liver transplantation has good long-term results in children.(c) 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.

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