• Bone Marrow Transplant. · May 1996

    Case Reports

    Acute mediastinitis secondary to leakage of parenteral nutrition from a migrated central venous catheter in a patient undergoing autologous bone marrow transplant.

    • Y K Keung, J Gendreau, A Barber, and E Cobos.
    • Division of Oncology@Hematology, Texas Tech University Health Sciences Center, Lubbock 79430, USA.
    • Bone Marrow Transplant. 1996 May 1;17(5):871-2.

    AbstractWe describe an unusual case of pyrexia of unknown origin in a patient undergoing autologous bone marrow transplantation for metastatic breast cancer. The fever was due to extravasation of lipid-containing hyperalimentation fluid from a migrated central venous catheter into the mediastinum, resulting in mediastinitis and pleurisy. The fever persisted despite broad-spectrum antibiotics and amphotericin B, and finally responded to steroids.

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