• Sleep medicine · Dec 2011

    Case Reports

    Morvan chorea and agrypnia excitata: when video-polysomnographic recording guides the diagnosis.

    • Federica Provini, Sara Marconi, Marcello Amadori, Pietro Guaraldi, Giulia Pierangeli, Pietro Cortelli, Elio Lugaresi, Pasquale Montagna, and Paolo Tinuper.
    • Department of Neurological Sciences, University of Bologna, Bologna, Italy. federica.provini@unibo.it
    • Sleep Med. 2011 Dec 1; 12 (10): 1041-3.

    IntroductionMorvan chorea is an antibody-mediated limbic encephalopathy characterized by severe insomnia, mental confusion, hallucinations, enacted dreams, hyperhidrosis, and neuromyotonia.Case DescriptionIn a 78 years old man presenting with progressive insomnia apathy and depression, a video-polysomnogram documented enacted dreams mimicking daily life activity (oneiric stupor). This finding led us to perform a search for serum antibodies to voltage-gated K+ channels, which was positive. A diagnosis of Morvan chorea was done. The patient underwent plasma exchange with complete resolution of the clinical picture.ConclusionsOneiric stupor may represent a useful precocious diagnostic marker in Morvan chorea.Copyright © 2011 Elsevier B.V. All rights reserved.

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