• Tareq Meyer and Manuel Dafotakis.
• Klinik für Neurologie, Uniklinik RWTH Aachen, Aachen, Deutschland.
• Dtsch. Med. Wochenschr. 2019 Feb 1; 144 (3): 203-206.

IntroductionA non-ketotic hyperglycaemia may cause an affection of basalganglia and, in the following, lead to a hemiballism-hemichorea movement-disorder.HistoryA 68-year-old male patient was admitted at our ward with a subacute and painless hemichorea-hemiballism movement-disorder.Findings And DiagnosisDue to elevated levels of glycated haemoglobin, negative ketone bodies in the urine and characteristic changes of the striatum in MR-imaging the diagnosis of a non-ketotic hyperglycemia induced hemichorea-hemiballism was made.Therapy And CourseAn antidiabetic treatment was applied using Metformin, Insulin glargin and Sitagliptin as well as a symptomatic treatment with Risperidon 3 mg. In the following, blood sugar levels normalized and a beginning regression of symptoms was observed.ConclusionsThe exact pathophysiology of this phenomenon is still not fully understood and will need to be investigated. Nevertheless, this disease should always be taken into consideration if the typical clinical presentation as well as matching laboratory tests and imaging features are found.© Georg Thieme Verlag KG Stuttgart · New York.

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